China (Mainland)
78628-80-5 Terbinafine Hydrochloride In China CAS NO.78628-80-5
- FOB Price: USD: 175.00-180.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,Other
- Available Specifications:
Medicine Grade(1-10)Kilogram Medicine Grade(10-500)Kilogram
- Product Details
Keywords
- 78628-80-5 Terbinafine Hydrochloride
- 78628-80-5 Terbinafine Hydrochloride exporter
- 78628-80-5 Terbinafine Hydrochloride In China
Quick Details
- ProName: 78628-80-5 Terbinafine Hydrochloride I...
- CasNo: 78628-80-5
- Molecular Formula: C21H26ClN
- Appearance: White Powder
- Application: Anti-fungal, onychomycosis Anti-tumor...
- DeliveryTime: 15 days
- PackAge: AS YOUR NEED
- Port: any port of China
- ProductionCapacity: 100 Kilogram/Day
- Purity: 99%min
- Storage: Cool and Dry
- Transportation: by sea or air
- LimitNum: 1 Kilogram
- Related Substances: Not detected
- Residue on Ignition: Complies
- Heavy Metal: Not detected
- Valid Period: 2 Years
- Molecular Weight: 327.891
- EINECS No: 245-385-8
Superiority
Hydrochlorothiazide (HCTZ), an orally active diuretic drug of the thiazide class, inhibits transforming TGF-beta/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel.
Hydrochlorothiazide is a diuretic drug of the thiazide class. Target: OthersHydrochlorothiazide belongs to thiazide class of diuretics. It reduces blood volume by acting on the kidneys to reduce sodium (Na) reabsorption in the distal convoluted tubule. The major site of action in the nephron appears on an electroneutral Na+-Cl? co-transporter by competing for the chloride site on the transporter. By impairing Na transport in the distal convoluted tubule, hydrochlorothiazide induces a natriuresis and concomitant water loss. Thiazides increase the reabsorption of calcium in this segment in a manner unrelated to sodium transport. Additionally, by other mechanisms, Hydrochlorothiazide is believed to lower peripheral vascular resistance
Details
Hydrochlorothiazide is a kind of thiazide diuretic drugs with moderate diuretic effect. It exert is diuretic effect through acting on the medullary ascending limb cortical segment, inhibiting the active re-absorption of Cl-and passive absorption of Na+ at this site. In addition, the product also has a hypotensive effect and anti-diuretic effect. It is suitable for treating a variety of edema, particularly for cardiogenic edema. It can also be used as antihypertensive agents, for treatment light, medium hypertension. It also has certain efficacy in treating diabetes insipidus, and idiopathic hypercalciuria. Commonly used thiazide diuretics include hydrochlorothiazide, chlorthalidone, indapamide and the like.
| Structure | |
| Catalog No. | SS-7511 |
| Name | Hydrochlorothiazide |
| CAS number | 58-93-5 |
| Related CAS | 121-25-5 |
| MFCD number | MFCD00051765 |
| Purity | 98% |
| Formula | C7H8ClN3O4S2 |
| FW | 297.7 |
| Storage | Room temperature |
| Shipping | Normal |