104376-79-6 Ceftriaxone Sodium In China CAS NO.104376-79-6

β -lactam antibiotic. Displays neuroprotective activity in vivo via upregulation and increased activity of the EAAT2 glutamate transporter.

Ceftriaxone is a third-generation, broad-spectrum cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. It has been shown to increase excitatory amino acid transporter-2 pump expression in the central nervous system and to reduce glutamatergic toxicity in both in vitro and in vivo models

Ceftriaxone, Disodium Salt, Hemiheptahydrate is used as an antibacterial agent. Ceftriaxone is used to study drug-induced immune hemolytic anemias prophylactic strategies to reduce neonatal encephalopathy pentylenetetrazole-evoked convulsions the effect of expression, binding, and inhibition of PDP1 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis. Ceftriaxone is a third-generation cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. It is effective against gram-positive and gram-negative bacteria. Ceftriaxone is thought to increase EAAT2 pump expression in the central nervous system and to reduce glutamatergic toxicity.

Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges, eyes, and inner ear. Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone is a commonly used antimicrobial due to its good activity against multi-drug resistant Enterobacteriaceae, its relatively safe adverse effect profile, and its long half-life which allows for the convenience of daily or twice-daily dosing.

• Product name

  Ceftriaxone disodium salt hemi(heptahydrate), beta-Lactam antibiotic

• Description

  β-Lactam antibiotic

• Biological description

  Potent β-lactam antibiotic. Effective against Gram-positive and Gram-negative bacteria. Neuroprotective effects in vivo.

• Purity

  > 98%

• CAS Number

  104376-79-6

• Chemical structure