69-53-4 Ampicillin Trihydrate Best price CAS NO.69-53-4

Ampicillin is a member of the extended-spectrum β-lactam family and similar in structure to penicillin. It is used in the selection of antibiotic cell hybrids and has a high rate of action against many gram-negative bacterial strains. Ampicillin sodium targets non-ESBL (Extended Spectrum β-lactamase) bacteria including Staphylococcus and Streptococcus species and medically important enteric pathogens such as Shigella and Salmonella. It has been found to be effective against certain β-lactam sensitive VRE or vancomycin resistant Enterococcus species. Resistance to ampicillin is routinely utilized as a selectable marker to confirm successful cell transformation.

Ampicillin is used as asemi-synthetic antibiotic which has antibacterial activity structurally related to penicillin. It is widely used selection reagent for transformed cells expressing β-lactamase. It is also used to prevent and treat a number of bacterial infections. It may also be used to prevent group B streptococcal infection in newborns.

Ampicillin is an antibacterial, orally active, semi-synthetic antibiotic that is structurally related to penicillin. Ampicillin belongs to the family of the α-aminobenzyl penicillin group, which differs from penicillin by an amino group that facilitates membrane penetration. A unique feature of Ampicillin is its ability to inhibit bacterial cell wall biogenesis. The action of Ampicillin is the interference directly of peptidoglycan biosynthesis, leading to structural instability and death of bacteria. In addition to its role as a broad-class antibiotic, Ampicillin can be used as a selective agent in several types of isolation media.